Malaria invasion in Red Blood Cell

RBC is single cell structure and it does not have nucleolus. Life span of RBC is around 115 days. Four  species  of malaria parasites are present one of them is Plasmodium falciparum, it enters into red blood cell (RBC). "Plasmodium falciparum malaria parasites have evolved several key-like molecules to enter into human red blood cells through different door-like host receptors. How does sporozoites enters the RBC to start their asexual life cycle. Life cycle of parasite in RBC is  two days to three days.

Dr Manoj Duraisingh researchers at Harvard T. H. Chan School of Public Health and the Broad Institute have identified a protein on cell wall of human red blood cells that serves as an essential entry point for invasion by the malaria parasite. This protein, called CD55, was found to be critical to the Plasmodium falciparum parasite's ability to attach itself to the red blood cell wall surface during invasion. The parasite has much way to attach on cell wall surface of RBC. One thing is must if CD55 is not present then parasite cannot attach to cell wall of RBC.

Team leader Dr Manoj Duraisingh says CD55 acts as door for malaria parasite. It acts door-like host receptors for many other parasites. If we able to shut this door or block CD55 we can control malaria.

Thus question arise all RBC have CD55 or for some time certain RBC has CD55. What is the utility or function of CD55? All invasion of parasite in RBC or any other cell wall is through CD55.

What about liver cell their cell wall also contain CD55. I do not know. How does invasion take place in liver cell?

I got this information from 

http://www.sciencedaily.com/releases/2015/05/150507145206.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fmalaria+%28Malaria+News+--+ScienceDaily%29

1.    Elizabeth S. Egan, Rays H.Y. Jiang, Mischka A. Moechtar, Natasha S. Barteneva, Michael P. Weekes, Luis V. Nobre, Steven P. Gygi, Joao A. Paulo, Charles Frantzreb, Yoshihiko Tani, Junko Takahashi, Seishi Watanabe, Jonathan Goldberg, Aditya S. Paul, Carlo Brugnara, David E. Root, Roger C. Wiegand, John G. Doench, Manoj T. Duraisingh. A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion. Science, May 2015 DOI: 10.1126/science.aaa3526